The Impact of Melatonin Supplementation and NLRP3 Inflammasome Deletion on Age-Accompanied Cardiac Damage

To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melatonin therapy. The results clarified the beginning o...

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Autores principales:	Ramy K. A. Sayed, Marisol Fernández-Ortiz, Ibtissem Rahim, José Fernández-Martínez, Paula Aranda-Martínez, Iryna Rusanova, Laura Martínez-Ruiz, Reem M. Alsaadawy, Germaine Escames, Darío Acuña-Castroviejo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2021-08-01
Colección:	Antioxidants
Materias:	cardiomyocytes NLRP3 inflammasome mitochondria CSA ultrastructure sarcopenia
Acceso en línea:	https://www.mdpi.com/2076-3921/10/8/1269
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