KCNK2-mediated regulation of MMP-2/9 by PlGF influences uterine artery function in pregnancy-induced hypertension

Abstract Background Pregnancy induced hypertension (PIH) is characterized by aberrant uterine arterial remodeling, a process tightly associated with an imbalance between placental growth factor (PlGF) and soluble fms like tyrosine kinase 1 (sFlt 1) as well as the down regulation of matrix metallopro...

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主要な著者:	Yinzhen Chen, Mingfu Chen, Ridong Zhou, Jichang Zheng, Gongxin Yang, Meiyu Chen, Jing Tu, Hongming Lin, Hu Zhao, Chen Lin, Xiaobin Chen
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-06-01
シリーズ:	BMC Pregnancy and Childbirth
主題:	Pregnancy-induced hypertension (PIH) Placental growth factor (PlGF) KCNK2 Matrix metalloproteinases (MMP-2/9) Uterine artery
オンライン･アクセス:	https://doi.org/10.1186/s12884-025-07743-5
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