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Case report: Severe asymptomatic hypertriglyceridemia associated with long-term low-dose rapamycin administration in a healthy middle-aged Labrador retriever

Rapamycin is an mTOR inhibitor that has been shown to extend the lifespan of laboratory model organisms. In humans, rapamycin is used at higher doses as an immunosuppressive medication to prevent organ rejection. Numerous adverse effects are seen with rapamycin treatment in humans, with one of the m...

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Autori principali: Jeremy B. Evans, Lucy Chou, Matt Kaeberlein, Daniel E.L. Promislow, Kate E. Creevy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-11-01
Serie:Frontiers in Veterinary Science
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Accesso online:https://www.frontiersin.org/articles/10.3389/fvets.2023.1285498/full
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