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Case report: Severe asymptomatic hypertriglyceridemia associated with long-term low-dose rapamycin administration in a healthy middle-aged Labrador retriever

Rapamycin is an mTOR inhibitor that has been shown to extend the lifespan of laboratory model organisms. In humans, rapamycin is used at higher doses as an immunosuppressive medication to prevent organ rejection. Numerous adverse effects are seen with rapamycin treatment in humans, with one of the m...

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Hlavní autoři: Jeremy B. Evans, Lucy Chou, Matt Kaeberlein, Daniel E.L. Promislow, Kate E. Creevy
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2023-11-01
Edice:Frontiers in Veterinary Science
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fvets.2023.1285498/full
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