Syringaldehyde Alleviates Cardiac Hypertrophy Induced by Hyperglycemia in H9c2 Cells Through GLP-1 Receptor Signals

<b>Background:</b> Cardiac hypertrophy is a significant complication of diabetes, often triggered by hyperglycemia. Glucagon-like peptide-1 (GLP-1) receptor agonists alleviate cardiac hypertrophy, but their efficacy diminishes under GLP-1 resistance. Syringaldehyde (SA), a natural phenolic compound,...

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Principais autores:	Yingxiao Li, Chao-Tien Hsu, Ting-Ting Yang, Kai-Chun Cheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-01-01
Colecção:	Pharmaceuticals
Assuntos:	AMPK cardiac hypertrophy diabetes complications GLP-1 resistance O-linked N-acetylglucosamine transferase (OGT) syringaldehyde
Acesso em linha:	https://www.mdpi.com/1424-8247/18/1/110
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