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Bolus Injection of Liraglutide Raises Plasma Glucose in Normal Rats by Activating Glucagon-like Peptide 1 Receptor in the Brain

Diabetes is commonly treated with glucagon-like peptide-1 receptor (GLP-1R) agonists including liraglutide and others. However, liraglutide was found to raise plasma glucose levels in normal rats. The current study aims to determine how liraglutide causes this contentious condition in rats, both nor...

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Principais autores: Chia-Chen Hsu, Juei-Tang Cheng, Ping Hao Hsu, Yingxiao Li, Kai-Chun Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-07-01
coleção:Pharmaceuticals
Assuntos:
liraglutide
Exendin-4
GLP-1 receptor
hypothalamic-pituitary-adrenal (HPA) axis
feeding behavior
rats
Acesso em linha:https://www.mdpi.com/1424-8247/15/7/904
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