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Mouse TAPBPR shows functional similarity to human TAPBPR in shaping the MHC-I immunopeptidome

Human TAPBPR is known to function as a Major Histocompatibility Complex class I (MHC-I) peptide exchange catalyst that shapes the peptide repertoire presented to immune cells. However, investigations characterizing TAPBPR from other species are limited. Here, we characterize mouse TAPBPR, exploring...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Juliana Bernardi Aggio, Marcel Wacker, William Guo, Arwen F. Altenburg, Ida Hafstrand, Reem Satti, Alison McDowall, Aure Aflalo, Andreas Neerincx, Jack Welland, Alice Abreu Torres, Mikkel-Ole Skjoedt, Karsten Skjødt, Jens Bauer, Juliane S. Walz, Louise H. Boyle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2026-04-01
Cyfres:Frontiers in Immunology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1756668/full
Tagiau: Ychwanegu Tag
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