Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance

Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting in ~219,000 deaths annually and a societal cost of ~USD60 billion. There are no antivirals or vaccines available to treat and/or prevent HuNoV. In this study, we performed a large-scale phenotypical antiviral scr...

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Bibliografiske detaljer

Principais autores:	Jana Van Dycke, Michela Puxeddu, Giuseppe La Regina, Eloise Mastrangelo, Delia Tarantino, Jasper Rymenants, Jessica Sebastiani, Marianna Nalli, Jelle Matthijnssens, Johan Neyts, Romano Silvestri, Joana Rocha-Pereira
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2021-09-01
Serier:	Pharmaceuticals
Fag:	<i>Caliciviridae</i> norovirus in vitro small molecule
Online adgang:	https://www.mdpi.com/1424-8247/14/10/1006
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