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In vivo targeted and deterministic single-cell malignant transformation

Why does a normal cell possibly harboring genetic mutations in oncogene or tumor suppressor genes becomes malignant and develops a tumor is a subject of intense debate. Various theories have been proposed but their experimental test has been hampered by the unpredictable and improbable malignant tra...

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Autori principali: Pierluigi Scerbo, Benjamin Tisserand, Marine Delagrange, Héloise Debare, David Bensimon, Bertrand Ducos
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2025-03-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/97650
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