Impact of changes in conventional risk factors induced by once-weekly GLP-1 receptor agonist exenatide on cardiovascular outcomes: an EXSCEL post hoc analysis

Abstract Background The objective of this study was to examine the degree to which conventional cardiovascular (CV) risk factor changes induced by once-weekly exenatide (EQW) might explain the placebo-controlled differences in CV outcomes observed in the Exenatide Study of Cardiovascular Event Lower...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ruth L. Coleman, Amanda I. Adler, Robert J. Mentz, Marat Fudim, Naveed Sattar, Rury R. Holman
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-08-01
Schriftenreihe:	Cardiovascular Diabetology
Schlagworte:	Glucagon-like peptide-1 receptor agonists Once-weekly exenatide Cardiovascular risk factors Cardiovascular outcomes Model simulation Mediation analyses
Online-Zugang:	https://doi.org/10.1186/s12933-025-02866-7
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!