Impact of changes in conventional risk factors induced by once-weekly GLP-1 receptor agonist exenatide on cardiovascular outcomes: an EXSCEL post hoc analysis

Abstract Background The objective of this study was to examine the degree to which conventional cardiovascular (CV) risk factor changes induced by once-weekly exenatide (EQW) might explain the placebo-controlled differences in CV outcomes observed in the Exenatide Study of Cardiovascular Event Lower...

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Principais autores:	Ruth L. Coleman, Amanda I. Adler, Robert J. Mentz, Marat Fudim, Naveed Sattar, Rury R. Holman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-08-01
coleção:	Cardiovascular Diabetology
Assuntos:	Glucagon-like peptide-1 receptor agonists Once-weekly exenatide Cardiovascular risk factors Cardiovascular outcomes Model simulation Mediation analyses
Acesso em linha:	https://doi.org/10.1186/s12933-025-02866-7
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