Lactate metabolism and lactylation in cardiovascular disease: novel mechanisms and therapeutic targets

Cardiovascular disease (CVD) is responsible for approximately 30% of annual global mortality rates, yet existing treatments for this condition are considered less than ideal. Despite being previously overlooked, lactate, a byproduct of glycolysis, is now acknowledged for its crucial role in the cell...

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Auteurs principaux:	Han Zhang, Jiulu Zhao, Jizhang Yu, Xi Zhang, Shuan Ran, Song Wang, Weicong Ye, Zilong Luo, Xiaohan Li, Yanglin Hao, Junjie Zong, Ran Li, Longyong Lai, Kexiao Zheng, Pinyan Huang, Cheng Zhou, Jie Wu, Yuan Li, Jiahong Xia
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-11-01
Collection:	Frontiers in Cardiovascular Medicine
Sujets:	lactate metabolism lactylation immune cell cardiovascular disease glycolysis
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcvm.2024.1489438/full
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