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Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium

Asthma exacerbations, a major concern in therapeutic strategies, are most commonly triggered by viral respiratory infections, particularly with human rhinovirus (HRV). Infection of bronchial epithelial (BE) cells by HRV triggers inflammation, notably monocyte recruitment. The increase of bronchial s...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Benoit Allard, Hannah Levardon, Pauline Esteves, Alexis Celle, Elise Maurat, Matthieu Thumerel, Pierre Olivier Girodet, Thomas Trian, Patrick Berger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-01-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
mucosal immunology
bronchial remodeling
asthma
monocyte
rhinovirus
epithelium
Online-Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2019.02998/full
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