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PolyI:C Upregulated CCR5 and Promoted THP-1-Derived Macrophage Chemotaxis via TLR3/JMJD1A Signalling

Objective: This study aimed to evaluate the specific roles of polyinosinic:polycytidylic acid (polyI:C) in macrophage chemotaxis and reveal the potential regulatory mechanisms related to chemokine receptor 5 (CCR5). Materials and Methods: In this experimental study, THP-1-derived macrophages (THP1...

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Principais autores: Xiaoxiao Yu, Huayang Wang, Hongjia Shao, Cuijuan Zhang, Xiuli Ju, Jie Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Royan Institute (ACECR), Tehran 2020-10-01
coleção:Cell Journal
Assuntos:
chemokine receptor 5
chemotaxis
macrophages
polyinosinic:polycytidylic acid
Acesso em linha:https://celljournal.org/journal/article/abstract/6713
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