Suppression of Autoimmune Arthritis by Small Molecule Inhibitors of the JAK/STAT Pathway
A skewed ratio of pro-inflammatory to anti-inflammatory cytokines, elevated growth factor synthesis and T- and B-lymphocyte activation are 3 hallmarks of rheumatoid arthritis (RA) pathology. Interleukin-6 (IL-6), IL-7, IL-17, IL-12/IL-23 and growth factors, granulocyte macrophage-colony stimulating...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2010-05-01
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| Col·lecció: | Pharmaceuticals |
| Matèries: | |
| Accés en línia: | http://www.mdpi.com/1424-8247/3/5/1446/ |
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