Vertical pathway inhibition of receptor tyrosine kinases and BAD with synergistic efficacy in triple negative breast cancer

Abstract Aberrant activation of the PI3K/AKT signaling axis along with the sustained phosphorylation of downstream BAD is associated with a poor outcome of TNBC. Herein, the phosphorylated to non-phosphorylated ratio of BAD, an effector of PI3K/AKT promoting cell survival, was observed to be correla...

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Manylion Llyfryddiaeth

Prif Awduron:	Yan Qin Tan, Yi-Shiou Chiou, Hui Guo, Shuwei Zhang, Xiaoming Huang, Dukanya Dukanya, Arun M. Kumar, Shreeja Basappa, Suling Liu, Tao Zhu, Basappa Basappa, Vijay Pandey, Peter E. Lobie
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Nature Portfolio 2024-01-01
Cyfres:	npj Precision Oncology
Mynediad Ar-lein:	https://doi.org/10.1038/s41698-023-00489-3
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