Vertical pathway inhibition of receptor tyrosine kinases and BAD with synergistic efficacy in triple negative breast cancer

Abstract Aberrant activation of the PI3K/AKT signaling axis along with the sustained phosphorylation of downstream BAD is associated with a poor outcome of TNBC. Herein, the phosphorylated to non-phosphorylated ratio of BAD, an effector of PI3K/AKT promoting cell survival, was observed to be correla...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Yan Qin Tan, Yi-Shiou Chiou, Hui Guo, Shuwei Zhang, Xiaoming Huang, Dukanya Dukanya, Arun M. Kumar, Shreeja Basappa, Suling Liu, Tao Zhu, Basappa Basappa, Vijay Pandey, Peter E. Lobie
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2024-01-01
סדרה:	npj Precision Oncology
גישה מקוונת:	https://doi.org/10.1038/s41698-023-00489-3
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!