Structural Insights into Novel 15-Prostaglandin Dehydrogenase Inhibitors
We discovered SW033291 in a high throughput chemical screen aimed at identifying 15-prostaglandin dehydrogenase (15-PGDH) modulators. The compound exhibited inhibitory activity in in vitro biochemical and cell-based assays of 15-PGDH activity. We subsequently demonstrated that this compound, and sev...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
MDPI AG
2021-09-01
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| Σειρά: | Molecules |
| Θέματα: | |
| Διαθέσιμο Online: | https://www.mdpi.com/1420-3049/26/19/5903 |
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