Inhibition of 15‐hydroxyprostaglandin dehydrogenase protects neurons from ferroptosis in ischemic stroke

Abstract Ischemic stroke is an acute serious cerebrovascular disease with high mortality and disability. Ferroptosis is an important regulated cell death (RCD) in ischemic stroke. 15‐Hydroxyprostaglandin dehydrogenase (15‐PGDH), a degrading enzyme of prostaglandin E2 (PGE2), is shown to regulate RCD...

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Principais autores:	Yunfei Xu, Kexin Li, Yao Zhao, Lin Zhou, Nina He, Haoduo Qiao, Qing Xu, Huali Zhang, Ying Liu, Jie Zhao
格式:	Artigo
語言:	Inglês
出版:	Wiley 2024-01-01
叢編:	MedComm
主題:	15‐PGDH ferroptosis GPX4 ischemic stroke PGE2
在線閱讀:	https://doi.org/10.1002/mco2.452
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