Discovery of oxazine-linked pyrimidine as an inhibitor of breast cancer growth and metastasis by abrogating NF-κB activation

IntroductionNuclear factor kappa (NF-κB) plays a key role in cancer cell proliferation; thus, small molecule inhibitors of NF-κB activity can effectively inhibit breast cancer (BC) progression. We have previously reported oxazine and piperazine-linked pyrimidines as novel anti-cancer agents that can...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Jie Yuan, Bhanuprakash C. Narasimhachar, Akshay Ravish, Li Yang, Hua Zhang, Qun Wang, Zhi Li, Jun Huang, Bei Wang, Geng Wang, Keshav Kumar Harish, Arunachalam Chinnathambi, Chandramohan Govindasamy, Mahendra Madegowda, Basappa Basappa
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2024-07-01
Sarja:	Frontiers in Oncology
Aiheet:	breast cancer nuclear factor-κB cell viability and motility TRX-01 oxazine linked pyrimidine NF-κB activation
Linkit:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1390992/full
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