Sample size recalculation in three-stage clinical trials and its evaluation
Abstract Background In clinical trials, the determination of an adequate sample size is a challenging task, mainly due to the uncertainty about the value of the effect size and nuisance parameters. One method to deal with this uncertainty is a sample size recalculation. Thereby, an interim analysis...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2024-09-01
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| シリーズ: | BMC Medical Research Methodology |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s12874-024-02337-9 |
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