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Misrepair in Context: TGFβ Regulation of DNA Repair

Repair of DNA damage protects genomic integrity, which is key to tissue functional integrity. In cancer, the type and fidelity of DNA damage response is the fundamental basis for clinical response to cytotoxic therapy. Here we consider the contribution of transforming growth factor-beta (TGFβ), a ub...

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Autori principali: Qi Liu, Kirsten Lopez, John Murnane, Timothy Humphrey, Mary Helen Barcellos-Hoff
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-08-01
Serie:Frontiers in Oncology
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Accesso online:https://www.frontiersin.org/article/10.3389/fonc.2019.00799/full
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