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Multienzymatic biotransformation of flavokawain B by entomopathogenic filamentous fungi: structural modifications and pharmacological predictions

Abstract Background Flavokawain B is one of the naturally occurring chalcones in the kava plant (Piper methysticum). It exhibits anticancer, anti-inflammatory and antimalarial properties. Due to its therapeutic potential, flavokawain B holds promise for the treatment of many diseases. However, due t...

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Principais autores: Paweł Chlipała, Tomasz Tronina, Monika Dymarska, Monika Urbaniak, Ewa Kozłowska, Łukasz Stępień, Edyta Kostrzewa-Susłow, Tomasz Janeczko
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-02-01
Series:Microbial Cell Factories
Acceso en liña:https://doi.org/10.1186/s12934-024-02338-9
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