Single-cell omics and flow cytometry identify distinct immune states of dural and brain-infiltrating IL-17-producing γδ T cells after experimental stroke

Abstract Background γδ T cells boost inflammatory responses and exacerbate tissue damage after ischemic stroke. However, the origin, dynamics, and tissue adaptation of γδ T cells in the ischemic brain and its border regions remain poorly understood. A systematic integration of large-scale datasets i...

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Autors principals:	Mingming Zha, Alina Jander, Haodi Cai, Marius Piepke, Karoline Degenhardt, Leo Winter, Tim Magnus, Mathias Gelderblom
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	Journal of Neuroinflammation
Matèries:	Acute ischemic stroke γδ T cell Dura Meninges ScRNAseq Flow cytometry
Accés en línia:	https://doi.org/10.1186/s12974-026-03794-3
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