Identification of a lactylation-related gene signature in microsatellite stable gastric cancer based on bulk and single-cell RNA-seq

BackgroundMicrosatellite stable (MSS) gastric cancer (GC) responds poorly to immunotherapy and exhibits heterogeneous outcomes. Histone lactylation plays a critical role in cancer progression. However, the prognostic and therapeutic potential of a lactylation-related gene signature (LRGS) in MSS GC...

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Bibliografiska uppgifter

Huvudupphov:	Zhong-Tai Lin, Yuan-Chun Chen, Li-Sheng You, Yuan-Zhao Wang, Xiang-Yu Wang, Liang-Jie Chi
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2026-05-01
Serie:	Frontiers in Immunology
Ämnen:	gastric cancer immunotherapy lactylation-related genes microsatellite stable single-cell analysis tumor microenvironment
Länkar:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1838771/full
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