Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation
Systemic hypoxia is characterized by peripheral vasodilation and pulmonary vasoconstriction. However, the system-wide mechanism for signaling hypoxia remains unknown. Accumulating evidence suggests that hemoglobin (Hb) in RBCs may serve as an O2 sensor and O2-responsive NO signal transducer to regul...
保存先:
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical investigation
2022-02-01
|
| シリーズ: | JCI Insight |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1172/jci.insight.155234 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|