Hypoxic vasodilatory defect and pulmonary hypertension in mice lacking hemoglobin β-cysteine93 S-nitrosylation
Systemic hypoxia is characterized by peripheral vasodilation and pulmonary vasoconstriction. However, the system-wide mechanism for signaling hypoxia remains unknown. Accumulating evidence suggests that hemoglobin (Hb) in RBCs may serve as an O2 sensor and O2-responsive NO signal transducer to regul...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical investigation
2022-02-01
|
| Serie: | JCI Insight |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1172/jci.insight.155234 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|