Ascophyllan Supplementation Is Safe and Associated with Exploratory Modulation of Innate Immune Phenotypes, Biochemical Parameters, and the Gut Microbiome in a Randomized Pilot Trial

Background: Ascophyllan, a sulfated polysaccharide extracted from brown seaweed, has shown immunomodulatory and antioxidant effects in preclinical studies, yet human clinical evidence remains scarce. This randomized, double-blind, placebo-controlled pilot trial evaluated the safety and exploratory b...

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Bibliografische Detailangaben

Hauptverfasser:	Shohei Mizuno, Jorge Luis Espinoza, Lam Quang Vu, Hirona Banno, Yusuke Iida, Saki Shinohara, Do Tung Dac, Yuya Nakagami, Kaori Uchino, Tomohiro Horio, Ichiro Hanamura, Nobuhiro Asai, Megumi Enomoto, Hiroya Tani, Takayuki Nakayama, Susumu Suzuki, Akiyoshi Takami
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-06-01
Schriftenreihe:	Marine Drugs
Schlagworte:	ascophyllan natural killer cells innate immunity gut microbiome functional dietary polysaccharide
Online-Zugang:	https://www.mdpi.com/1660-3397/24/6/213
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