TICAM-1/TRIF associates with Act1 and suppresses IL-17 receptor–mediated inflammatory responses
TICAM-1/TRIF, a TLR3 adaptor molecule, associates with Act1 to inhibit the interaction between IL-17RA and Act1, resulting in attenuated IL-17-mediated inflammatory responses. TICAM-1 (also called TRIF) is the sole adaptor of TLR3 that recognizes double-stranded RNA. Here, we report that TICAM-1 is...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2022-02-01
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| coleção: | Life Science Alliance |
| Acesso em linha: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101181 |
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