Long-term HBsAg clearance, relapse, and safety following tenofovir or entecavir discontinuation in non-cirrhotic, HBeAg-negative chronic hepatitis

Abstract Stopping nucleos(t)ide analogues (NAs) can foster hepatitis B surface antigen (HBsAg) clearance, yet comparative data for tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are scarce. We compared HBsAg loss, virological relapse (VR), clinical relapse (CR), and safety after stopping TD...

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Autori principali:	Onuma Sattayalertyanyong, Wimolrak Bandidniyamanon, Julajak Limsrivilai, Watcharasak Chotiyaputta, Supot Nimanong, Tawesak Tanwandee
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-02-01
Serie:	Scientific Reports
Soggetti:	Hepatitis B Chronic Hepatitis B surface antigens Entecavir Tenofovir Withholding treatment
Accesso online:	https://doi.org/10.1038/s41598-026-40972-y
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