Histone deacetylase 3 promotes innate antiviral immunity through deacetylation of TBK1

Abstract TANK-binding kinase 1 (TBK1), a core kinase of antiviral pathways, activates the production of interferons (IFNs). It has been reported that deacetylation activates TBK1; however, the precise mechanism still remains to be uncovered. We show here that during the early stage of viral infectio...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Jie-lin Tang, Qi Yang, Chong-hui Xu, He Zhao, Ya-ling Liu, Can-yu Liu, Yuan Zhou, Dong-wei Gai, Rong-juan Pei, Yun Wang, Xue Hu, Bo Zhong, Yan-yi Wang, Xin-wen Chen, Ji-zheng Chen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Oxford University Press 2020-08-01
סדרה:	Protein & Cell
נושאים:	TBK1 HDAC3 deacetylation IRF3 innate immune
גישה מקוונת:	https://doi.org/10.1007/s13238-020-00751-5
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!