Properdin Modulates Complement Component Production in Stressed Human Primary Retinal Pigment Epithelium Cells

The retinal pigment epithelium (RPE) maintains visual function and preserves structural integrity of the retina. Chronic dysfunction of the RPE is associated with retinal degeneration, including age-related macular degeneration (AMD). The AMD pathogenesis includes both increased oxidative stress and...

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Detalhes bibliográficos

Principais autores:	Nicole Schäfer, Hannah N. Wolf, Anne Enzbrenner, Juliane Schikora, Maria Reichenthaler, Volker Enzmann, Diana Pauly
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-08-01
coleção:	Antioxidants
Assuntos:	retinal pigment epithelium complement system properdin AMD-risk genotype intracellular cell-associated
Acesso em linha:	https://www.mdpi.com/2076-3921/9/9/793
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