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Complement C1s deficiency in a male Caucasian patient with systemic lupus erythematosus: a case report

Deficiencies of the early complement components of the classical pathway (CP) are well-documented in association with systemic lupus erythematosus (SLE) or SLE-like syndromes and severe pyogenic infections. Among these, complete C1s deficiency has been reported in nine cases so far. Here, we describ...

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Main Authors: Jessica S. Kleer, Lillemor Skattum, Denise Dubler, Ingeborg Fischer, Armin Zgraggen, Esther Mundwiler, Min Jeong Kim, Marten Trendelenburg
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
immunodeficiency diseases
complement C1s
non-sense mutation
systemic lupus erythematosus (SLE)
lupus nephritis (LN)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1257525/full
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