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Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis

Abstract Background Dysregulation of the B-cell activating factor (BAFF) system is involved in the pathogenesis of systemic lupus erythematosus (SLE). Increased serum concentrations of BAFF are related to lupus nephritis and disease activity among SLE patients. Recently, a variant of the BAFF-encodi...

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Principais autores: Justa Friebus-Kardash, Marten Trendelenburg, Ute Eisenberger, Camillo Ribi, Carlo Chizzolini, Uyen Huynh-Do, Karl Sebastian Lang, Benjamin Wilde, Andreas Kribben, Oliver Witzke, Sebastian Dolff, Cornelia Hardt
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-11-01
Serier:BMC Nephrology
Fag:
BAFF-var allele
TNFSF13B
Systemic lupus erythematosus
Lupus nephritis
Disease activity
Swiss SLE cohort study (SSCS)
Online adgang:http://link.springer.com/article/10.1186/s12882-019-1623-4
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