A Cassette Vector System for the Rapid Cloning and Production of Bispecific Tetravalent Antibodies
Bivalent single chain (sc)Fv-Fc antibodies have been used for years as recombinant alternatives of natural immunoglobulins. We have extended this approach to the scFv-Fc-scFv antibody format to obtain tetravalent antigen binding and the possibility to generate bispecific antibodies. We developed a m...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2012-04-01
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| coleção: | Antibodies |
| Assuntos: | |
| Acesso em linha: | http://www.mdpi.com/2073-4468/1/1/19 |
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