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Methodological validation of a cryo-TEM-based detection method for empty capsid ratio in recombinant adeno-associated virus

Recombinant adeno-associated virus (rAAV) is one of the most promising vectors for gene therapy. It consists of a protein capsid that encapsulates the genetic material. However, during the production process, except for the full particles containing the genome, a variety of types of particles are al...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Lingyi Xu, Jinhuan Chen, Wei Zhu, Yaokun Zhao, Fangfang Zheng, Rong Du, Yuwei Jiang, Yidan Yang, Yuanyuan Chen, Yuanshu Dong, Zhengxi Zhang, Yong Tong
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2026-03-01
Rangatū:Biochemistry and Biophysics Reports
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2405580825004844
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