CDK5 promotes apoptosis and attenuates chemoresistance in gastric cancer via E2F1 signaling

Abstract Background Chemoresistance is a major clinical challenge that leads to tumor metastasis and poor clinical outcome. The mechanisms underlying gastric cancer resistance to chemotherapy are still unclear. Methods We conducted bioinformatics analyses of publicly available patient datasets to es...

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Bibliografische Detailangaben

Hauptverfasser:	Long-Long Cao, Yu-Kai Wu, Tong-Xin Lin, Mi Lin, Yu-Jing Chen, Ling-Qian Wang, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Hua-Long Zheng, Jian-Wei Xie, Ping Li, Chang-Ming Huang, Chao-Hui Zheng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-11-01
Schriftenreihe:	Cancer Cell International
Schlagworte:	Apoptosis CDK5 Chemoresistance Gastric cancer
Online-Zugang:	https://doi.org/10.1186/s12935-023-03112-4
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