CDK5 promotes apoptosis and attenuates chemoresistance in gastric cancer via E2F1 signaling

Abstract Background Chemoresistance is a major clinical challenge that leads to tumor metastasis and poor clinical outcome. The mechanisms underlying gastric cancer resistance to chemotherapy are still unclear. Methods We conducted bioinformatics analyses of publicly available patient datasets to es...

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Библиографические подробности

Главные авторы:	Long-Long Cao, Yu-Kai Wu, Tong-Xin Lin, Mi Lin, Yu-Jing Chen, Ling-Qian Wang, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Hua-Long Zheng, Jian-Wei Xie, Ping Li, Chang-Ming Huang, Chao-Hui Zheng
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2023-11-01
Серии:	Cancer Cell International
Предметы:	Apoptosis CDK5 Chemoresistance Gastric cancer
Online-ссылка:	https://doi.org/10.1186/s12935-023-03112-4
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