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Decreased expression of GEM in osteoarthritis cartilage regulates chondrogenic differentiation via Wnt/β-catenin signaling

Abstract Background GEM (GTP-binding protein overexpressed in skeletal muscle) is one of the atypical small GTPase subfamily members recently identified as a regulator of cell differentiation. Abnormal chondrogenesis coupled with an imbalance in the turnover of cartilaginous matrix formation is high...

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Bibliografski detalji
Glavni autori: Lu Gan, Zhonghao Deng, Yiran Wei, Hongfang Li, Liang Zhao
Format: Artigo
Jezik:Inglês
Izdano: BMC 2023-10-01
Serija:Journal of Orthopaedic Surgery and Research
Teme:
Online pristup:https://doi.org/10.1186/s13018-023-04236-z
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