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Cuprorivaite microspheres inhibit cuproptosis and oxidative stress in osteoarthritis via Wnt/β-catenin pathway

This study aims to evaluate the therapeutic potential of cuprorivaite microspheres for osteoarthritis (OA), in particular, potential molecular mechanisms were investigated. The microspheres were developed from Ca(NO3)2•4H2O, Cu(NO3)2•3H2O, and silica gel, and further therapeutic effects were tested...

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Principais autores: Bo Li, Tongmeng Jiang, Juan Wang, Hongping Ge, Yaqi Zhang, Tong Li, Chen Wang, Weiguo Wang
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-12-01
Series:Materials Today Bio
Assuntos:
Osteoarthritis
Cuprorivaite microspheres
Cuproptosis
Oxidative stress
Wnt/β-catenin pathway
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2590006424003612
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