Research progress of base editing and prime editing tools based on the CRISPR/Cas system

The base editor (BE) and prime editing guide RNA (pegRNA)-based prime editor (PE) technologies relying on the CRISPR/Cas system are very efficient gene editors that have been developed in recent years. The BEs include cytosine base editors (CBEs) that mediate the conversion of C to T, adenine base e...

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Autors principals:	Herui Gao, Song Gao, Guoshi Kan, Leonid N. Valentovich, Yingfeng An
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-12-01
Col·lecció:	Molecular Therapy: Nucleic Acids
Matèries:	MT: RNA/DNA Editing adenine base editors CRISPR cytosine base editor glycosylase base editor prime editing
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2162253125003257
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