PlexinD1 is a driver and a therapeutic target in advanced prostate cancer

Abstract Aggressive prostate cancer (PCa) variants associated with androgen receptor signaling inhibitor (ARSI) resistance and metastasis remain poorly understood. Here, we identify the axon guidance semaphorin receptor PlexinD1 as a crucial driver of cancer aggressiveness in metastatic castration-r...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jing Wei, Jing Wang, Wen Guan, Jingjing Li, Tianjie Pu, Eva Corey, Tzu-Ping Lin, Allen C Gao, Boyang Jason Wu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2025-01-01
Цуврал:	EMBO Molecular Medicine
Нөхцлүүд:	Castration-resistant Prostate Cancer Cellular Plasticity Neuroendocrine Differentiation Androgen Receptor Signaling inhibitors PlexinD1
Онлайн хандалт:	https://doi.org/10.1038/s44321-024-00186-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!