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An Anti-Tumor Vaccine Against Marek's Disease Virus Induces Differential Activation and Memory Response of γδ T Cells and CD8 T Cells in Chickens

Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-cell lymphomas and serves as a natural virus-induced tumor model in chickens. The most efficacious vaccine, CVI988/Rispens (CVI988), against MD has been used for several decades. However, the mechanisms leading t...

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Päätekijät: Xiaoli Hao, Shuai Li, Jiaqi Li, Yi Yang, Aijian Qin, Shaobin Shang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021-02-01
Sarja:Frontiers in Immunology
Aiheet:
γδ T cell
CD8 T cell
immune response
MDV
vaccine
Linkit:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645426/full
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