Unraveling new characteristics of γδ T cells using scRNA-seq in TCR KO chicken

Abstract The characterization of T cells in chickens has proven to be challenging, primarily due to the lack of specific markers to differentiate classical Th1, Th2, and Th17 subsets. Furthermore, chickens possess a notably high proportion of γδ T cells, making them a unique model for investigating...

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Autores principales:	Theresa von Heyl, Milena Brunner, Antonia Schmauser, Christine Wurmser, Simon Früh, Benjamin Schusser
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2026-03-01
Colección:	BMC Genomics
Materias:	T cells Chicken Gamma/delta T cells Genetically modified animals ScRNA-seq
Acceso en línea:	https://doi.org/10.1186/s12864-026-12741-8
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