Phosphoproteomic Profiling Reveals Overlapping and Distinct Signaling Pathways in <i>Dictyostelium discoideum</i> in Response to Two Different Chemorepellents

Chemorepulsion mechanisms for eukaryotic cells are poorly understood. We performed proteomics and phosphoproteomics to elucidate how <i>Dictyostelium discoideum</i> responds to its two endogenous chemorepellent signals, the protein AprA and inorganic polyphosphate (polyP). AprA and polyP affected le...

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Hauptverfasser:	Salman Zahir Uddin, Ramesh Rijal, Darrell Pilling, Richard H. Gomer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-12-01
Schriftenreihe:	Cells
Schlagworte:	proteomics phosphoproteomics <i>Dictyostelium discoideum</i> chemorepulsion small GTPases AprA
Online-Zugang:	https://www.mdpi.com/2073-4409/15/1/60
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