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Phosphoproteomic Profiling Reveals Overlapping and Distinct Signaling Pathways in <i>Dictyostelium discoideum</i> in Response to Two Different Chemorepellents

Chemorepulsion mechanisms for eukaryotic cells are poorly understood. We performed proteomics and phosphoproteomics to elucidate how <i>Dictyostelium discoideum</i> responds to its two endogenous chemorepellent signals, the protein AprA and inorganic polyphosphate (polyP). AprA and polyP affected le...

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Principais autores: Salman Zahir Uddin, Ramesh Rijal, Darrell Pilling, Richard H. Gomer
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-12-01
Series:Cells
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Acceso en liña:https://www.mdpi.com/2073-4409/15/1/60
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