Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the ‘POPulation differences in VACcine responses’ (POPVAC) programme

Introduction Drivers of lower vaccine efficacy and impaired vaccine-specific immune responses in low-income versus high-income countries, and in rural compared with urban settings, are not fully elucidated. Repeated exposure to and immunomodulation by parasite infections may be important. We focus o...

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Main Authors:	Pontiano Kaleebu, Emily Webb, Moses Muwanga, Gyaviira Nkurunungi, Ludoviko Zirimenya, Agnes Natukunda, Jacent Nassuuna, Gloria Oduru, Caroline Ninsiima, Christopher Zziwa, Florence Akello, Robert Kizindo, Mirriam Akello, Anne Wajja, Henry Luzze, Stephen Cose, Alison M Elliott, Alison Elliott, Rebecca Amongin, Beatrice Nassanga, Irene Nambuya, Prossy Kabuubi, Emmanuel Niwagaba, Grace Kabami, Helen Akurut, Alex Mutebe, Milly Namutebi, Caroline Onen, Esther Nakazibwe, Josephine Tumusiime, Susan Amongi, Moses Sewankambo, Denis Nsubuga, Samuel Kiwanuka, Fred Kiwudhu, David Abiriga, Moses Kizza, Samsi Nansukusa, Hermelijn Smits, Maria Yazdanbakhsh, Govert van Dam, Paul Corstjens, Sarah Staedke, James Kaweesa, Edridah Tukahebwa, Elly Tumushabe, Prossy N Kabuubi, Joel Serubanja, Sarah G Staedke
Format:	Artigo
Language:	Inglês
Published:	BMJ Publishing Group 2021-02-01
Series:	BMJ Open
Online Access:	https://bmjopen.bmj.com/content/11/2/e040427.full
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