Exploring the active ingredients and potential mechanisms of Pingchan granules in Parkinson’s disease treatment through network pharmacology and transcriptomics

Abstract Parkinson’s disease (PD), the second most prevalent neurodegenerative disorder, poses significant challenges to single-target therapeutic strategies due to its complex etiology. This has driven interest in multi-target approaches, particularly those leveraging natural compounds. Pingchan gr...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Qiu-Han Xu, Yi-Ling Wang, Cheng Wang, Si-Si Jiang, Bao-Rong Zhang, Jun Tian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-03-01
coleção:	Scientific Reports
Assuntos:	Parkinson’s disease Pingchan granules Network Pharmacology Single-cell nuclear sequencing Molecular dynamics simulation Mendelian randomization
Acesso em linha:	https://doi.org/10.1038/s41598-025-91344-x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!