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LncRNA KCNQ1OT1 Secreted by Tumor Cell-Derived Exosomes Mediates Immune Escape in Colorectal Cancer by Regulating PD-L1 Ubiquitination via MiR-30a-5p/USP22

Background: This study tried to explore the mechanism of long non-coding RNA (lncRNA) KCNQ1OT1 in tumor immune escape.Methods: Gene Expression Omnibus (GEO) and microarray analysis were used to screen the differentially expressed lncRNA and microRNA (miRNA) in normal tissues and tumor tissues. Quant...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Di Xian, Liangbo Niu, Jie Zeng, Lei Wang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2021-07-01
Rangatū:Frontiers in Cell and Developmental Biology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fcell.2021.653808/full
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