Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway

Osteoarthritis is a worldwide joint disease caused by abnormal chondrocytic metabolism. However, traditional therapeutic methods aimed at anti-inflammation for early-stage disease are palliative. In the present study, we demonstrated that cepharanthine (CEP), extracted from the plant Stephania cepha...

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Detalhes bibliográficos

Principais autores:	Minjun Yao, Caihua Zhang, Lingzhi Ni, Xiaoxiao Ji, Jianqiao Hong, Yazhou Chen, Jie Wang, Congsun Li, Jiyan Lin, Tingting Lu, Yihao Sheng, Menghao Sun, Mingmin Shi, Chenhe Zhou, Xunzi Cai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-06-01
coleção:	Frontiers in Pharmacology
Assuntos:	cepharanthine chondrocytes osteoarthritis MAPK NF-κB autophagy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2022.854239/full
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